The XIAO ESP32 Sense does not have any mechanical provisions for mounting the board, the camera, and the antenna. All the components are fragile and without something to hold everything together, there is the possibility of damage. In addition, all the components get very warm during use.

I designed a holder for the board, the camera, and the antenna. I added a small fan to provide some airflow around the components. I printed the base from Prusament PETG and the antenna retainer from generic PLA. The board and the camera get so hot that PLA can melt. I had some considerable stringing with the PETG material, but a couple of minutes with a deburring tool, a jackknife, and a heat gun removed all the string material. I used painted grid supports in PrusaSlicer to support the bridge areas and printed it on my Prusa MK3S.

I soldered stacking headers to the Perma-Proto board and header pins on the ESP32 board. I inserted the board into the header pins which makes the board removable and also allows space for a heatsink on the underside of the board.

I wired the fan directly to the 5V pin and the ground pin on the ESP32. I might add a switch to it so the fan noise doesn't disturb audio recordings when using the microphone on the ESP32 Sense.

Here are links to purchased components:

ESP32 Sense Board:
https://www.digikey.com/en/products/detail/seeed-technology-co-ltd/113991115/18724504?_gl=1*1pc1iyj*_up*MQ..&gclid=CjwKCAjw0sfHBhB6EiwAQtv5qWTphaYdvN1pLL-wEgJzH2zYU194fiL8NOLMA0-MlQpU69ccPF9EFRoC_EMQAvD_BwE&gclsrc=aw.ds

OV5640 Camera:
https://www.digikey.com/en/products/detail/seeed-technology-co-ltd/114993115/21277047?_gl=1*1oh8t1i*_up*MQ..&gclid=CjwKCAjw0sfHBhB6EiwAQtv5qWTphaYdvN1pLL-wEgJzH2zYU194fiL8NOLMA0-MlQpU69ccPF9EFRoC_EMQAvD_BwE&gclsrc=aw.ds

5V Fan:
https://www.amazon.com/dp/B0CFKYVVXL?ref=ppx_yo2ov_dt_b_fed_asin_title

Perma-Proto Board;
https://www.adafruit.com/product/1214?srsltid=AfmBOorNea6mBwYk3MNeadu6hgp0QS4qsZvsYxJtafNR5X3_S1XOgZfn

You'll also need 2mm X 14 screws and 2 2mm nuts to attach the fan to the printed base.